Novel multi-drugs incorporating hybrid-structured nanofibers enhance alkylating agent activity in malignant gliomas

Shih-Jung Liu,Shun Tai Yang,Shu Mei Chen,Yin-Chen Huang,Wei Hwa Lee,Jui Ho,Yin Chun Chen,Yuan-Yun Tseng

Novel multi-drugs incorporating hybrid-structured nanofibers enhance alkylating agent activity in malignant gliomas

2019

Shih-Jung Liu
Shun Tai Yang
Shu Mei Chen
Yin-Chen Huang
Wei Hwa Lee
Jui Ho
Yin Chun Chen
Yuan-Yun Tseng

Background:Malignant gliomas (MGs) are highly chemotherapy-resistant. Temozolomide (TMZ) and carmustine (BiCNU) are alkylating agents clinically used for treating MGs. However, their effectiveness ...

Keywords:

Pharmacology
Medicine
Nanofiber
nanofibrous membrane
Temozolomide
Carmustine

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