Effect of immunomodulators on certain haematological parameters in ameliorating bovine Endometritis

In the present investigation seventy two endometritic cows selected from some parts of Odisha and West Bengal after meticulous screening and were allotted randomly into six equal groups (n=12). Group I, II and III animals were administered with 100µg of E. coli LPS (LPS), 500 mg of oyster glycogen (OG), and 1000 mg enrofloxacin through i.u route after reconstituted with 30 milliliter of Phosphate Buffer Saline (PBS). Oral herbal drugs were used in group IV animals. In group V,50 ml of normal saline was infused i.u. Endometritis animals receiving no treatments were considered as control for the study. Blood sample was collected from experimental cows prior to institution of therapy, 24 hrs after treatment and at next Estrus for evaluation of different haematological parameters. Use of immunomodulators improved Hb concentration Significantly (p < 0.05) at post treatment succeeding estrous. A significantly lower (p < 0.05) mean TLC value was observed at succeeding estrus in group I and II than other treatment groups. mean Nutrophil value at 24 hrs of treatment increased significantly (p < 0.05) from pretreatment value and it decreased significantly at the next succeeding etrous.