[Follow-up of high-dose chemotherapy treated patients using bone marrow scintigraphy with Tc-99m nanocolloids.]

We assessed bone marrow hematopoetic capacity before and after high dose chemotherapy (HDC) by means of Tc-99m nanocolloid bone marrow scintigraphy (EMS). Quantitative and qualitative BMS was performed in patients previously treated with standard chemotherapy and presently submitted to HDC. In this sequential study, each patient was his own control. All three quantification parameters increased in a statistically significant way from aplasia to a higher value in bone marrow recovery, in all patients. Thus we believe that quantification could help to exclude some patients with low bone marrow capacity from HDC.