An efficient and reusable PdCl 2 /TBAF system for the Heck reaction under ligand- and solvent-free conditions

PdCl2 combined with TBAF (n-Bu4NF) were found to be efficient conditions for the Heck reactions. In the presence of PdCl2 and TBAF, a variety of aryl halides were coupled with alkenes smoothly in moderate to good yields. Moreover, the PdCl2/TBAF system could be recovered and reused several times in the reaction. Note that these reactions are conducted under solvent-free, ligand-free and reusable conditions.