Advances in effector protein of histone methylation

As a significant epigenetic regulation mechanism, histone methylation plays an important role in many biologi- cal processes. In cells, there are various histone methyltransferases and histone demethylases working cooperatively to regulate the histone methylation state. Upon histone modification, effector proteins recognize modification sites specifically, and affect gene transcriptional process. This review mainly focuses on recent advances in histone methylation effector pro- tein's function mechanism.