Two-micron laser resection of the prostate-tangerine technique for the treatment of large-volume prostate

Objective:To evaluate the clinical efficiency and safety of two-micron laser resection of the prostate-tangerine technique(TmLRP-TT) for the treatment of large-volume( 70 ml) prostate in patients with benign prostatic hyperplasia( BPH).Methods:This retrospective analysis included 80 BPH patients with the prostatic volume larger than 70 ml,all treated by TmLRP-TT.We comparatively analyzed the levels of hemoglobin and serum sodium before and after surgery,recorded intra-and post-operative complications,and followed up the patients at 6 and 12 months after operation for International Prostate Symptom Score(IPSS),quality of life(QOL),maximum flow rate(Qmax),and postvoid residual urine volume(PVR). Results:All the operations were successfully completed. The mean hemoglobin decreased(0. 68 ± 0. 43) g /dl intraoperatively,but no apparent reduction was observed in serum sodium. Lower urinary tract symptoms were relieved significantly in all the cases. At 12 months after surgery,IPSS was decreased by73. 89% as compared with the baseline(20. 03 ± 6. 9 vs 5. 23 ± 3. 59),QOL by 64. 55%(4. 09 ± 1. 19 vs 1. 45 ± 1. 36),and PVR by 79. 30%(97. 31 ± 57. 90 vs 20. 14 ± 24. 20 ml),while Qmax increased by 140. 42%([8. 04 ± 3. 62]vs [19. 33 ± 3. 28]ml /s).The incidence of complications was low either intraoperatively or during the 12 months after operation. Conclusion:TmLRP-TT is a safe and effective surgical endoscopic approach to the treatment of large-volume prostate in BPH patients.