Clinical characteristics and outcomes for patients with thymic carcinoma: Evaluation of Masaoka staging.

7603 Background: Thymic carcinomas (TC) are rare cancers with limited data regarding outcomes, particularly for those patients (pts) with advanced disease. Methods: We identified pts with TC diagnosed between 1993-2012. Pt characteristics, recurrence free survival (RFS) from date of resection, and overall survival (OS) from date of diagnosis were analyzed. Pts were followed until death or last follow up. Time-to-event outcomes were determined using the Kaplan-Meier method. Results: 121 pts with TC were identified with 7 pts (6%) with Masaoka stage I, 13 (11%) with stage II, 25 (21%) with stage III, 13 (11%) with stage IVA, 61 (51%) with stage IVB, and 2 (2%) with unclear staging. Higher Masaoka stage was associated with worse OS and RFS (5-yr OS of 100%, 81%, 51%, 24%, and 17% for stage I, II, III, IV respectively, p<0.001 and 5-yr RFS of 80%, 28%, and 7% for stage I/II, III, and IV respectively, p<0.001). Stage IVB pts with lymph node involvement had a better 5-year OS as compared to stage IVB pts with d...