Method of manufacturing a pharmaceutical drug delivery instrument

While can be inserted under the skin painlessly, providing pharmaceutical drug delivery instrument which can be carried out efficiently pharmaceutical drug administration or blood extracted by suction. A base, a through-hole path through the surface from the back surface of the base portion, a substantially conical convex portion of the plurality of fine provided in alignment to the base, provided in the convex portion, the convex portion proximal side and a convex portion pharmaceutical drug delivery instrument characterized in that it comprises a fluid guide groove for guiding the fluid between the tip.