Human brain meningioma tumor detection using visible resonance Raman spectroscopy

Meningiomas are the most common brain neoplasms. They often show a wide distribution of locations and morphological attributes. Therefore, rendering tumor margin status is difficult during surgery. Accurate identification of tumor boundary intraoperatively is essential for total tumor removal and adjacent healthy tissue preservation. Visible resonance Raman (VRR) spectroscopy has been used for detection and diagnosis of human organ lesions since 2011. Here, we report for the first time the preliminary results on the evaluation of a VRR-LRRTM analyzer based on VRR technique to identify human brain meningioma grades and margins.