NLRP3 inflammasome mediates oxidative stress-induced pancreatic islet dysfunction

Marina Sokolova,Afaf Sahraoui,Merete Høyem,Jonas Øgaard,Egil Lien,Pål Aukrust,Arne Yndestad,Trine Ranheim,Hanne Scholz

NLRP3 inflammasome mediates oxidative stress-induced pancreatic islet dysfunction

2018

Marina Sokolova
Afaf Sahraoui
Merete Høyem
Jonas Øgaard
Egil Lien
Pål Aukrust
Arne Yndestad
Trine Ranheim
Hanne Scholz

Inflammasomes are multiprotein inflammatory platforms that induce caspase-1 activation and subsequently interleukin (IL)-1β and IL-18 processing. The NLRP3 inflammasome is activated by different fo...

Keywords:

Endocrinology
Internal medicine
Pancreatic islets
Diabetes mellitus
Interleukin
Inflammasome
Oxidative stress
Biology
Islet

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