Helicobacter pylori Peptidyl Prolyl Isomerase Expression Is Associated with the Severity of Gastritis

Purpose Helicobacter pylori secretory peptidyl prolyl isomerase, HP0175, is progressively identified as a pro-inflammatory and pro-carcinogenic protein, which serves to link H. pylori infection to its more severe clinical outcomes. Here, we have analyzed host HP0175-specific antibody responses in relation to the severity of gastritis.