REACTIVITY SINGLE WALLED CARBON NANOTUBES UNDER INTERACTION WITH BIOLOGICAL MOLECULES – DNA AND PROTEINS

Literature review of experimental and calculated data on non-covalent interaction of DNA and proteins with nonfunctional carbon nanotubes was done in the paper. The results on characterization of single walled carbon nanotubes with Raman spectroscopy and conformation analysis of main biological polymers – DNA and protein of bovine serum albumin (BSA) under interaction with single walled carbon nanotubes with SEIRA (surface enhanced infrared absorption) was presented.   The experiments give a possibility to conclude about non-covalent interaction in the complex nanotube-biomolecule. Analysis of the experimental data have proved that under DNA interaction with nanotubes, the bounding of DNA occurs at the nanotube surface, forming stable complex with Van-der-Vaalse interaction . In this case, -stacking has a main role with intra H-bond reconstruction biomolecules. We suppose, that albumin adsorption on nanotube surface takes place with participation of conventional cite interaction for BSA, due to hydrophobic interaction and -stacking. Experimental data on structural reconstruction of albumin is an evidence of this fact.