A reusable biosensor for detecting mercury(II) at the subpicomolar level based on “turn-on” resonance light scattering

A reusable sensing strategy employing magnetic nanoparticles and thymine-containing aptamers was developed to detect Hg2+ in real water samples based on “turn-on” resonance light scattering. The LOD was as low as 500 fM (S/N = 3), and the present sensor can be repeatedly used for at least seven cycles.