Abstract 17119: Substrate Stiffness Alters Human Induced Pluripotent Stem Cell-derived Cardiomyocyte Differentiation And Maturation

Yutao Xi,Sheng’an Su,Fernanda Mesquita,Camila Hochman-Mendez,Po-Feng Lee,Shuiping So,Jianhua. Gu,Jie Cheng,Luiz C. Sampaio,Meixiang Xiang,Doris A. Taylor

Abstract 17119: Substrate Stiffness Alters Human Induced Pluripotent Stem Cell-derived Cardiomyocyte Differentiation And Maturation

2019

Yutao Xi
Sheng’an Su
Fernanda Mesquita
Camila Hochman-Mendez
Po-Feng Lee
Shuiping So
Jianhua. Gu
Jie Cheng
Luiz C. Sampaio
Meixiang Xiang
Doris A. Taylor

Background: Progressively increasing myocardial stiffness occurs during heart development, remodeling and aging, and plays a significant role in heart disease. The mechanisms underlying the effects...

Keywords:

myocardial stiffness
Heart development
Cardiomyocyte differentiation
Cell biology
Fibrosis
Electrophysiology
Induced pluripotent stem cell
Heart disease
Medicine
substrate stiffness

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