Measles, mumps and rubella immunisation in children at risk of infection with Human Immunodeficiency Virus

Summary A retrospective serological study of 81 children at risk of HIV (11 HIV-infected, 70 HIV-negative) was performed to assess susceptibility to measles, mumps and rubella and response to measles, mumps and rubella (MMR) immunisation. There was no difference in the initial serological response between the HIV-infected and HIV-negative children. Repeat serology should be performed on HIV-infected children as during follow-up antibodies may be lost. Reimmunisation should be considered for the seronegative.