Intracranial delivery of recombinant nerve growth factor : Release kinetics and protein distribution for three delivery systems

Purpose. Three different polymeric delivery systems, composed of either poly(ethylene-co-vinyl acetate) (EVAc) or poly(lactide-co-gly-colide) (PLGA), were used to administer recombinant human nerve growth factor (rhNGF) intracranially in rats.