Application of Electro-Oxidative a-Cyanation of Aza-Rings to the Synthesis of Gephyrotoxin 223AB

Six and five-membered cyclic α-cyanoamines have been prepared effici- ently from N-benzylpiperidine and N-benzylpyrrolidine. These α-cyano- amines were successfully used in the synthesis of gephyrotoxin 223AB