Operative time for severe multiple fractures

Objective To discuss the operative time for patients with severe multiple fractures by observing indexes including C reactive protein(CPR),creatine kinase(CK),MB isoenzyme of creatine kinase(CKMB),blood glucose(GLU),etc..Methods Patients with ISS ≥16 were included in our study,observing indexes involving blood pressure,respiratory rate,temperature,PaO2.The concentrations of CPR,CK,CKMB,GLU,etc.in peripheral blood were detected at post-injury day 1,3,7 and 14,respectively.Finally,operation was performed till their vital signs became stable and the indexes such as CPR,CK,CKMB,GLU became normal or approached to normal level after 1-2 days.Results Totally 29 patients were followed up,8 of whom were followed up by phone calls.The follow-up time ranged from 9 to 24 months.Damage control operation controlled bleeding and contamination in the majority of patients,and achieved a good recovery postoperatively.All of 10 open fractures and 13 closed fractures indicated no infection of incision following internal fixation.Conclusion The vital signs and indexes such as SpO2,CPR,CK,CKMB,GLU can be used as the objective indexes to determine the optemal time for performing orthopedics operation.