Antistress Activity of Tinospora Cordifolia with Application of Yoga

Aim: Mental stress can lead to various biochemicals, physiological and psychological changes in human body. The present study was designed to evaluate the antistress activities of Tinospora cordifolia (wild) Miers associated with yoga Methods:  A randomized double blind placebo control 8 weeks study was conducted. The mental stress patients were diagnosed clinically by using different validated psychological rating scales. A total of 63 patients with mental stress were randomized into four groups. The antistress activities of the treatments were measured by different psychological rating scales as well as various biochemical parameters i.e. lipid profile, serum glucose concentration. Results:  The serum glucose, lipid like triglyceride, cholesterol, ldl –cholesterol and psychological parameters like anxiety, depression were significantly increases in patients with chronic mental stress. However following treatment with Tinospora cordifolia associated with practice of yoga significantly reduced various stress induced psychological and biochemical parameters (P< 0.001) Conclusion:  The findings of the clinical study suggested that Tinospora cordifolia and practice of yoga have significant anti stress activities as shown by its mitigating effects on chronic stress induced psychological and biochemical perturbation comparable to that induced by well known adaptogenic agent diazepam.