Responsiveness of Irradiated Rat Anterior Pituitary Cells to Hypothalamic Releasing Hormones Is Restored by Treatment with Growth Hormone

Andrea Chiarenza,Laurence Lempereur,Tullio Palmucci,Giuseppina Cantarella,M. Amico-Roxas,Vincent Goffin,Paolo Murabito,Gaetano Magro,Renato Bernardini

Responsiveness of Irradiated Rat Anterior Pituitary Cells to Hypothalamic Releasing Hormones Is Restored by Treatment with Growth Hormone

2000

Andrea Chiarenza
Laurence Lempereur
Tullio Palmucci
Giuseppina Cantarella
M. Amico-Roxas
Vincent Goffin
Paolo Murabito
Gaetano Magro
Renato Bernardini

Hypopituitarism is a common sequela of irradiation in cancer patients. Here we report that recombinant human growth hormone (r-hGH) prevents cell death and restores secretory capacity of irradiated ra

Keywords:

Somatotropic cell
Adrenocorticotropic hormone
Endocrinology
Gonadotropin
Anterior pituitary
Follicle-stimulating hormone
Corticotropic cell
Luteinizing hormone
Internal medicine
Biology
Hypopituitarism
Prolactin
Programmed cell death
Cancer

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