Quantitative evaluation of the ultrastructural restructurings of the adrenal cortex of rats under stress after preliminary administration of corticotropin

: Submicroscopic changes in the adrenal cortex in dynamics of stress reaction development following preliminary corticotropin injection are characterized by less pronounced variations in quantitative parameters of basic structural components of parenchyma and stroma and are combined with stabilization of the 11-HCS level in blood and phasic effacement of general adaptogenic syndrome. The adaptogenic effect of the preparation at the organism level is observed with an accompanying increase in the adrenal cortex resistance to the influence of extreme factors.