Radiotracers for different angiogenesis receptors in a melanoma model

Early and reliable diagnosis of melanoma, a skin tumorwith a poor prognosis, is extremely important. Phagedisplay peptide libraries are a convenient screeningresource for identifying bioactive peptides that interact withcancer targets. The aim of this study was to evaluate twotechnetium-99m tracers for angiogenesis detection in amelanoma model, using cyclic pegylated pentapeptide withRGD and NGR motifs conjugated with the bifunctionalchelator mercaptoacetyltriglycine (MAG