Neoadjuvant volumetric modulated arc radiochemotherapy with a simultaneous integrated boost technique for the treatment of locally advanced rectal cancer

Locally advanced rectal cancer includes cancers which are extending through the rectal wall and/or regional lymph nodes are involved. Preoperative chemoradiotherapy with radiation doses up to 45-50 Gy and radical transabdominal surgery are considered as best treatment options in such cases, but dose escalation to the gross tumor using simultaneous integrated boost technique has been introduced recently. We present a case of locally advanced rectal cancer treated with simultaneous integrated boost, capecitabine and surgical intervention.