Detection and quantification of acidic drug residues in South African surface water using gas chromatography-mass spectrometry.
2017
Abstract A method was optimized for derivatization, separation, detection and quantification of salicylic acid, acetylsalicylic acid, nalidixic acid, ibuprofen, phenacetin, naproxen, ketoprofen, meclofenamic acid and diclofenac in surface water using gas chromatography-mass spectrometry. For most of the acidic drugs, recovery was in the range 60–110% and the percent standard deviation was below 15% for the entire method, with limits of detection ranging from 0.041 to 1.614 μg L −1 . The developed method was applied in the analysis of acidic drugs in Umgeni River system, KwaZulu-Natal South Africa. All of the selected acidic drugs were detected and quantified, their concentration in Umgeni River system ranged from 0.0200 to 68.14 μg L −1 .
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
65
References
57
Citations
NaN
KQI