Kinetic study of benzyl sulfamide synthesis by thermolysis of N-(benzyl)-N´-(tert-butoxycarbolyl) sulfamide

In this investigation, a kinetic study of the thermolysis of N -(benzyl)- N ´-( tert -butoxycarbonyl) sulfamide to yield benzylsulfamide in an efficient manner was performed. The thermolysis reaction was monitored in helium flow by thermogravimetry at different heating rates between 0.2 and 10 o C/min. The activation energy value was obtained from the Kissinger-Akahira-Sunose isoconversional method and theoretical calculations (from Transition State Theory). The reaction model of the process was studied by means of the master-plot method. Results obtained from experiments of thermolysis performed under the melting point temperature of N -(benzyl)- N ´-( tert -butoxycarbonyl) sulfamide fit with an Avrami-Erofeev model whereas data found for experiments at higher temperatures fit with first order model. Isothermal experiments were simulated at 115, 120 and 130 o C using the model-free method, employing only the activation energy value.