Study the release kinetics of curcumin released from PVA/curcumin composites and its evaluation towards hepatocarcinoma.

curcumin from the prepared composites was found to be 2.739X10 -2 , 1.638X10 -2 , and 5.777X10 -4 in basic, acidic and neutral solution respectively according to Higuch's equation. The results of the in/vitro cytotoxic activity of the released curcumin showed sustained antiproliferative potency up to 30 % growth inhibition against the human liver cancer cell line (HEPG2) which extended to 25 days, to overcome hepatocarcinoma.