One-carbon metabolism and CpG island methylator phenotype status in incident colorectal cancer : a nested case-referent study

Bethany Van Guelpen,Anna M. Dahlin,Johan Hultdin,Vincy Eklöf,Ingegerd Johansson,Maria L. Henriksson,Inger Cullman,Göran Hallmans,Richard Palmqvist

One-carbon metabolism and CpG island methylator phenotype status in incident colorectal cancer : a nested case-referent study

2010

Bethany Van Guelpen
Anna M. Dahlin
Johan Hultdin
Vincy Eklöf
Ingegerd Johansson
Maria L. Henriksson
Inger Cullman
Göran Hallmans
Richard Palmqvist

OBJECTIVE: We related prediagnostic plasma folate, vitamin B12, and total homocysteine concentrations, and the MTHFR 677C>T and 1298A>C polymorphisms, to the risk of colorectal cancer with an ...

Keywords:

Methylenetetrahydrofolate reductase
Gynecology
Oncology
Colorectal cancer
DNA methylation
Vitamin B12
Homocysteine
Carcinogenesis
Immunology
CpG Island Methylator Phenotype
Polymorphism (computer science)
Internal medicine
Medicine
Methylation

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