Minimum Alveolar Concentration of Isoflurane and Arterial Blood Gas Values in Anesthetized Green Iguanas, Iguana iguana

ABSTRACT The minimum alveolar concentration of isoflurane (MACisoflurane) was determined in seven green iguanas, Iguana iguana, using a standard double bracketing technique. Following chamber induction, anesthesia was maintained with isoflurane in 100% O2 using mechanical ventilation of 25 ml/kg body weight, at a rate of two breaths per minute. Following an equilibration period of 25 min at each percentage of isoflurane tested, response to a supramaximal electrical stimulus applied to the ventral portion of the tail was assessed. Arterial blood was collected from the right carotid artery for determining blood gas values in iguanas maintained at 1.5 times their individual MACisoflurane. As measured by time to loss of righting reflex, chamber induction time was 23 ± 7 min (range 18 – 35 min). Mean (±SD) MACisoflurane was 1.62 ± 0.40%, median MAC was 1.60 %, with a range of 1.10 to 2.15%. Values for pH, partial pressure of carbon dioxide (PaCO2) in kPa (mmHg), partial pressure of oxygen (PaO2) in kPa (mmHg),...