A PheWAS study of a large observational epidemiological cohort of African Americans from the REGARDS study

Xueyan Zhao,Xin Geng,Vinodh Srinivasasainagendra,Ninad S. Chaudhary,Suzanne E. Judd,Virginia G. Wadley,Orlando M. Gutiérrez,Henry E. Wang,Ethan M. Lange,Leslie A. Lange,Daniel Woo,Frederick W. Unverzagt,Monika M. Safford,Mary Cushman,Nita A. Limdi,Rakale Collins Quarells,Donna K. Arnett,Marguerite R. Irvin,Degui Zhi

A PheWAS study of a large observational epidemiological cohort of African Americans from the REGARDS study

2019

Xueyan Zhao
Xin Geng
Vinodh Srinivasasainagendra
Ninad S. Chaudhary
Suzanne E. Judd
Virginia G. Wadley
Orlando M. Gutiérrez
Henry E. Wang
Ethan M. Lange
Leslie A. Lange
Daniel Woo
Frederick W. Unverzagt
Monika M. Safford
Mary Cushman
Nita A. Limdi
Rakale Collins Quarells
Donna K. Arnett
Marguerite R. Irvin
Degui Zhi

Background Cardiovascular disease, diabetes, and kidney disease are among the leading causes of death and disability worldwide. However, knowledge of genetic determinants of those diseases in African Americans remains limited.

Keywords:

Cohort
Bioinformatics
Observational study
Kidney disease
Disease
Biology
Human genetics
Diabetes mellitus
Epidemiology
Single-nucleotide polymorphism
Genome-wide association study
Demography

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