Heteroaromatic derivative and application thereof to medicament

The present invention provides a heteroaromatic derivative or a stereoisomer, a geometric isomer, a tautomer, a nitrogen oxide, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, and a pharmaceutical composition containing the compound provided by the invention. The present invention also discloses application of the compound or pharmaceutical composition thereof in the preparation of medicaments for the treatment of respiratory diseases, particularly chronic obstructive pulmonary disease (COPD).