Anticoagulation strategies in the perioperative period for lung transplant

Abstract Lung Transplant (LTx) patients may require systemic anticoagulation in the perioperative period for various indications at the time of the procedure. 4-factor prothrombin complex concentrate has been approved in the US to reverse warfarin's effects for patients requiring urgent surgery. We describe a perioperative anticoagulation strategy with warfarin that is reversed prior to incision using 4 factor complex concentrate (4-FPCC) for off-pump LTx patients.