GUT MICROBIOTA AND BILE ACIDS METABOLISM AT THE CROSSROAD BETWEEN CHOLESTEROL HOMEOSTASIS AND CHRONIC INFLAMMATION IN ENDOTHELIAL DYSFUNCTION AND ARTERIAL STIFFNESS

The gut microbiota has been implicated as an environmental factor that modulates atherosclerosis, and recent evidence suggests that microbiota-mediated changes in bile acid profiles and signalling through the bile acid nuclear receptor farnesoid X receptor (FXR) contribute to impaired endothelial