Inheritance of the Rh Complex ‘Santi’, R̂ou(GV)1

. The Rh reactions of blood samples from members of a Negro family in which the ‘Santi’ complex occurs are presented. The ‘Santi’ complex is characterized by a weak expression of D, G and V, and failure to produce hrs and the ‘e-like’ antigen defined by the Santiago serum. The complex is inherited in a straightforward manner although the possibility remains that the altered expression of the D, G and V antigens results from the action of an Rh-linked or built-in modifier.