Effect of combination immunotherapy on tumor growth, survival, and intratumoral immune infiltration in transgenic murine model of melanoma.

Robyn Gartrell,Zoe Blake,Camden L Esancy,Rolando Perez-Lorenzo,Emanuelle Rizk,Yichun Fu,Chen Yang,Yvonne M. Saenger

Effect of combination immunotherapy on tumor growth, survival, and intratumoral immune infiltration in transgenic murine model of melanoma.

2018

Robyn Gartrell
Zoe Blake
Camden L Esancy
Rolando Perez-Lorenzo
Emanuelle Rizk
Yichun Fu
Chen Yang
Yvonne M. Saenger

e21610Background: Talimogene Laherparepvec (T-Vec), a modified Herpes Simplex Type I (HSV I) virus, is the first oncolytic virus to be FDA approved for the treatment of cancer. T-Vec has two propos...

Keywords:

Melanoma
Immune system
Cancer research
Transgene
Pathology
Immunotherapy
Medicine
Virus
murine model
Talimogene laherparepvec
immune infiltration
Oncolytic virus
Cancer

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