Food Allergy Sensitization and Presentation in Siblings of Food-Allergic Children

RS Gupta, MM Walkner, M Greenhawt. J Allergy Clin Immunol Pract. 2016;4(5):956–962 To determine the prevalence of food sensitization and clinical food allergy among siblings of food-allergic children. Children were enrolled as part of the Chicago Family Cohort Food Allergy study. Eligible families had 1 index child with confirmed food allergy and at least 1 sibling participating in the study. There were 478 food-allergic children and 642 siblings. Of index children, 63.6% were male, and 50% were between the ages of 2 and 5 years. Of siblings, 66.5% were younger than the index child. A structured questionnaire-based interview was performed with each parent. Serum IgE (sIgE) values for 9 common food allergens …