Gut microbial signatures associated with moxidectin treatment efficacy of Haemonchus contortus in infected goats

Abstract Parasitic infections are associated with profound changes in the structure and function of the gut microbiome in various host-parasite systems. Here we examined the microbial composition and function in the abomasum, proximal colon and feces of Haemonchus contortus-infected goats after a partial anthelmintic drug clearance. A single-dose treatment of H. contortus-infected goats with Cydectin (moxidectin) resulted in an 83.9% and 61.8% reduction in fecal egg counts (EPG) and worm burden, respectively (P