Total-Body PET/MRI in Oncological Applications

One potential advantage of adding PET to MRI is that PET in oncology is the fact that it is routinely a whole-body (skull base to mid-thighs) and sometimes a total-body (vertex to toes) examination. Total-body indications include sarcomas, melanoma, multiple myeloma, cutaneous lymphomas, and evaluation of skeletal metastases [1, 2]. Hybrid positron emission tomography/magnetic resonance imaging (PET/MRI) is one of the multimodality technologies that provides both biological and morphological information of lesions [3, 4]. Compared to PET/CT, advantages of PET/MRI include reduction of radiation exposure, use of MRI to assess organ function, and improvement of diagnostic ability due to better contrast of MRI [5–7].