Evaluation of clinical outcomes by analysis of mutations in tumor tissue and circulating plasma DNA using next-generation sequencing (NGS) from STEAM, a prospective, randomized, multicenter study in metastatic colorectal cancer (mCRC).

John Lee,John F. Palma,Lijing Yao,Alexander F. Lovejoy,Stephanie Yaung,David Zhang,Nasiema Wingate-Pearse,May Yau,Carolyn Williams,Monica Pimentel,Abraham Munoz,Katrina Mayol,Christoph Mancao,Alan Nicholas,Nicolas Sommer,Johanna C. Bendell,Herbert Hurwitz,Ulrich-Peter Rohr

Evaluation of clinical outcomes by analysis of mutations in tumor tissue and circulating plasma DNA using next-generation sequencing (NGS) from STEAM, a prospective, randomized, multicenter study in metastatic colorectal cancer (mCRC).

2017

John Lee
John F. Palma
Lijing Yao
Alexander F. Lovejoy
Stephanie Yaung
David Zhang
Nasiema Wingate-Pearse
May Yau
Carolyn Williams
Monica Pimentel
Abraham Munoz
Katrina Mayol
Christoph Mancao
Alan Nicholas
Nicolas Sommer
Johanna C. Bendell
Herbert Hurwitz
Ulrich-Peter Rohr

11510Background: STEAM (NCT01765582) assessed the efficacy and safety of concurrent (c) and sequential (s) FOLFOXIRI-bevacizumab (BEV) vs FOLFOX-BEV for first-line treatment of mCRC. Methods: The A...

Keywords:

DNA
DNA sequencing
Pathology
Colorectal cancer
Medicine
tumor tissue
Oncology
plasma dna
multicenter study
Internal medicine

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