Asymmetric Hydrosilane Reduction of Ketones Catalyzed by an Iridium Complex Bearing a Hydroxyamide-Functionalized NHC Ligand.

Shun Kawabata,Hiromu Tokura,Hiroyuki Chiyojima,Masaki Okamoto,Satoshi Sakaguchi

Asymmetric Hydrosilane Reduction of Ketones Catalyzed by an Iridium Complex Bearing a Hydroxyamide-Functionalized NHC Ligand.

2012

Shun Kawabata
Hiromu Tokura
Hiroyuki Chiyojima
Masaki Okamoto
Satoshi Sakaguchi

The air- and moisture-stable isoleucinol-derived iridium carbene complex IRI in combination with AgBF4 efficiently catalyzes the stereoselective reduction of a variety of acetophenone derivatives and analogues at room temperature.

Keywords:

Combinatorial chemistry
Catalysis
Carbene
Acetophenone
Iridium
Stereoselectivity
Ligand
Organic chemistry
Chemistry

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations