The prognostic value of multilineage dysplasia in de novo acute myeloid leukemia patients with intermediate-risk cytogenetics is dependent on NPM1 mutational status.

To the editor: The prognostic significance of multilineage dysplasia (MLD) in acute myeloid leukemia patients with intermediate-risk cytogenetics (IR-AML) presenting as de novo disease is unclear.[1][1]–[4][2] Falini et al have recently analyzed the biologic and prognostic significance of MLD in