Local Heat Increases Blood Flow and Oxygen Tension in Wounds

• The effect of local hyperthermia on subcutaneous tissue oxygen tension (Psqo 2 ) and perfusion was investigated in eight patients (13 trials) using a subcutaneously implanted oxygen tonometer. Application of heat increased subcutaneous tissue temperature and Psqo 2 . Mean Psqo 2 during oxygen breathing rose by 39.5 mm Hg, an 80% increase over the average baseline Psqo 2 . The corresponding mean subcutaneous temperature increased 4.0°C. A significant linear correlation was found between the change in Psqo 2 and subcutaneous temperature. There was an average threefold increase in local perfusion estimated by using the Fick principle. The data reaffirm the value of local hyperthermia in treating contaminated wounds and suggest a mechanism for its ability to ameliorate infections. The mechanism implies that local heat may have prophylactic value as well. ( Arch Surg 1987;122:221-225)