Regiochemistry of the Rearrangement of Cyclohexenyl and Cyclohexadienyl Phosphates to β-Keto Phosphonates.

Diethyl vinyl phosphates derived from substituted cyclohexanones are known to rearrange to β-keto phosphonates upon treatment with excess LDA. To develop strategies for the regiocontrol of this rearrangement, the effect of regiospecific preparation of the vinyl phosphate has been tested and the use of dienyl phosphates has been studied