Abstract 15646: Contraction Force Analysis Using Optical Imaging in Normal and Mybpc3-Mutated iPSC-Derived Cardiomyocytes Grown on Matrices With Tunable Stiffness

Introduction: Mutations in MYBPC3 (Myosin Binding Protein C) underlie 40% of hypertrophic cardiomyopathy cases in The Netherlands. MYBPC3 codes for the thick filament associated protein cardiac myo...