Hepatitis B in persons infected with the human immunodeficiency virus in Porto-Novo: prevalence and associated factors

Introduction: Approximately 5 to 25% of the 34 million people living with HIV (PLHIV) worldwide are co-infected with HBV or HCV. The objective of this work is to determine the prevalence of HBsAg in PLHIV followed at the University Hospital of Porto-Novo and to identify the factors associated with this co-infection. Methods: This was a descriptive and analytical cross-sectional study covering the period from 01/02/2016 to 01/05/2016. We included PLHIV on antiretroviral therapy (ARV) or not, who were older than 15 years and who gave their consent. HBsAg was investigated by the DiaSpot One-Step Test Strip Rapid Test. Results: 301 PLHIV participated in the study. The average age was 42 ± 10.3 years old. The age groups 35-45 (39.2%) and 25-35 (23.9%) were the most represented. Women (73.1%) were predominant. The main common risk factors were unprotected sex (98%), multiple sexual partnership (57.5%), circumcision outside hospital (66.7% of men), scarification (78.1%) and transfusion (17.6%). The prevalence of HBs Antigenemia was 14.3%. Factors associated with co-infection were history of liver disease and alanine aminotransferase levels greater than twice normal. Conclusion: The prevalence of HBsAg is high among our PLHIV. The search for this Ag should be systematic during the initial assessment of these patients in order to adapt the ARV treatment.