Comparing different imaging modalities in harada disease: a case report.

Harada disease is considered to be a cell-mediated autoimmune disease directed against melanocytes. It is a multisystem disorder characterized by granulomatous panuveitis with exudative retinal detachments that is often associated with neurologic and cutaneous manifestations. In the past, stereoscopic fluorescein angiography was one of the most widely used diagnostic techniques for confirming the level of retinal detachment in Harada. Currently, optical coherence tomography (OCT), a non-invasive test, is becoming more commonly used than fluorescein angiography in demonstrating the axial distribution of the fluid.1 Fundus autofluorescence (FAF) and infrared (IR) imaging are newer modalities for imaging of the retinal pigment epithelium (RPE) and deeper outer retinal structures. Spectral illumination with different wavelengths permits visualization of pathologies, which may not be apparent under visible light. Herein, we compare all available imaging techniques for the detection of fluid distribution in a Harada case.