Anatomic and pharmacokinetic properties of intravitreal bevacizumab and ranibizumab after vitrectomy and lensectomy.

John B Christoforidis,Michelle M. Williams,Jillian Wang,Angela Jiang,Cedric Pratt,Mahmoud Abdel-Rasoul,George H. Hinkle,Michael V. Knopp

Anatomic and pharmacokinetic properties of intravitreal bevacizumab and ranibizumab after vitrectomy and lensectomy.

2013

John B Christoforidis
Michelle M. Williams
Jillian Wang
Angela Jiang
Cedric Pratt
Mahmoud Abdel-Rasoul
George H. Hinkle
Michael V. Knopp

Purpose To determine the anatomic characteristics and pharmacokinetic properties of intravitreally placed bevacizumab and ranibizumab after pars plana lensectomy or pars plana vitrectomy and to compare these with nonoperated control eyes in a rabbit model.

Keywords:

Ranibizumab
Surgery
Pars plana
Bevacizumab
Ophthalmology
Vitrectomy
Metabolic clearance rate
Pars plana lensectomy
Pharmacokinetics
Medicine
rabbit model
intravitreal bevacizumab

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