Eine modellnahe Ausgleichsfunktion für die radiometrische Insulinbestimmung durch Rücktitration freier Antikörper

In the radiometric estimation of insulin with 125I insulin radioreagent first an equilibrium is established between insulin antibodies and insulin of the test samples. Thereafter 125I insulin binds to free antibodies in a kinetically controlled reaction. The bound activity may be fitted to the equations of this model without contradictions. But they were proved to be not useful for practical data evaluation. A modelnear equations is given, the three parameter of which may be estimated by iterative nonlinear regression analysis without complications.