Textural features of hypoxia PET predict survival in head and neck cancer during chemoradiotherapy

A Sörensen,M. Carles,H. Bunea,Liette Majerus,Christian Stoykow,Nils H. Nicolay,N. Wiedenmann,P. Vaupel,Philipp T. Meyer,Anca-Ligia Grosu,M. Mix

Textural features of hypoxia PET predict survival in head and neck cancer during chemoradiotherapy

2019

A Sörensen
M. Carles
H. Bunea
Liette Majerus
Christian Stoykow
Nils H. Nicolay
N. Wiedenmann
P. Vaupel
Philipp T. Meyer
Anca-Ligia Grosu
M. Mix

Purpose The aim of this study was to investigate whether textural features of tumour hypoxia, assessed with serial [18F]fluoromisonidazole (FMISO)-PET, were able to predict clinical outcome in patients with head and neck squamous cell carcinoma (HNSCC, T1-4, N+, M0) during chemoradiotherapy (CRT).

Keywords:

Radiomics
Head and neck cancer
Medicine
Head and neck squamous-cell carcinoma
Radiology
FMISO
Hypoxia (medical)
Chemoradiotherapy
Fluorodeoxyglucose
Hazard ratio
Coefficient of variation
Nuclear medicine

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