Intravascular histiocytosis associated with rheumatoid arthritis Romatoid artrit ile ilişkili intravasküler histiyositoz

Various dermatoses associated with rheumatoid arthritis (RA). have been described Recently, a specific skin lesion termed “intravascular histiocytosis” has been proposed as a new entity among these dermatoses. We report a 58-year-old man with an 8-years history of RA who presented with numerous variable sized erythematous papules, plaques and nodules on the V region of the neck, right femoral region and bilateral shins. Histopathological examination of these lesions demonstrated intraluminal aggregates mainly composed of CD68-positive histiocytes in markedly dilated vessels. In addition, after 6 months of follow-up, the patient was diagnosed as Kaposi sarcoma (KS) for another skin lesion. We discuss the pathogenesis of this association and compare with other cases reported in the literature. Pam Med J 2013;6(2):92-95