Avaliação da colesterolenia não HDL em escolares e adolescentes

2015 
Objetivo: avaliar os niveis sericos de nao HDL-colesterol (nao HDL-c) e perfil lipidico em jovens entre seis e 19 anos. Metodo: estudo descritivo transversal e descritivo. As variaveis foram: colesterol total e fracoes, nao HDL-c, triglicerides e IMC. Excluiram-se portadores de doenca ou em uso de farmaco que alterem o perfil lipidico e pacientes com triglicerides > 400 mg/dL. Utilizado SPSS-17 para analise das variaveis. Resultados: participaram 108 jovens, sendo 63 do genero feminino. Na amostra total, a media de nao HDL-c foi 114,7 mg/dL e de LDL-c 94,9 mg/dL. Nao houve diferenca significativa dos valores de nao HDL-c e LDL-c entre os generos e faixa etaria. No estudo, o LDL-c e o nao HDL-c tiveram forte correlacao entre si R= 0,864 e com o colesterol total R= 0,890 e R= 0,907, respectivamente. O LDL-c correlacionou-se negativamente com VLDL-c. O nao HDL-c correlacionou-se positivamente com VLDL-c e triglicerides.Quanto ao IMC, 3,7% estavam abaixo do normal, 49,1% eutroficos, 23,1% com sobrepeso e 24,1% obesos. Pacientes obesos apresentaram niveis significativamente maiores de nao HDL-c, VLDL-c e TG e nivel menor de HDL-c em relacao aos eutroficos. Os valores de nao HDL-c correspondentes aos percentis 75 e 95 foram 129 e 157 mg/ dL, respectivamente. Conclusao: nao HDL-c obteve melhor correlacao que o LDL-c com diferentes variaveis lipidicas e foi melhor parâmetro na avaliacao lipidica em pacientes obesos. Assim, o nao HDL-c mostrou-se metodo confiavel e promissor para investigar dislipidemias em escolares e adolescentes. Objective: to evaluate the serum levels of non-HDL-cholesterol (non-HDL-c) and lipid profile in young people between six and 19 years old. Method: this was a cross-sectional and descriptive, and descriptive study. The variables were: total cholesterol and fractions, non-HDL-c, triglycerides, and BMI. Those with disease or using drugs that alter the lipid profile, and patients with triglycerides > 400 mg/dL were excluded from the study. SPSS- 17 was used for the analysis of variables. Results: 108 young people participated; 63 females. The average of non-HDL-c was 114.7 mg/dL and LDL-c 94.9 mg/dL. There was no significant difference between the values of non-HDL-c and LDL-c between genders and age groups. LDL-c and non-HDL-c showed strong correlation, R = 0.864 and total cholesterol R= 0.890 and R= 0.907, respectively. LDL-c negatively correlated with VLDL-c. Non-HDL-c positively correlated with VLDL-c and triglycerides. The IMC results showed that 3.7% were below normal, 49.1% eutrophic, 23.1% overweight, 24.1% obese. Obese patients showed significantly higher levels of non-HDL-c, VLDL-c, and TG and lower levels of HDL-c compared to eutrophics. The values of non-HDL-c corresponding to 75 and 95 percentiles were 129 and 157 mg/dL, respectively. Conclusion: non-HDL-c showed better correlation than LDL-c with different lipid variables and was the best parameter for lipid assessment in obese patients. Thus, non-HDL-c showed to be a reliable and promising method of investigating dyslipidemias in schoolchildren and teenagers.
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